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Let's delve into the topic together. Understanding Prescription Requirements: Spironolactone is a potent medication that can have significant effects on hormone … Spironolactone is a "water pill" (diuretic) that causes you to make more urine. This helps your body get rid of extra water and salt. Spironolactone also helps treat or prevent low blood potassium levels and blocks the activity of a certain natural substance (aldosterone) that can cause edema. ALDACTONE® (spironolactone) medication page for patients to search for scientific information & prescribing information about Pfizer medications in the US. Save on Aldactone (spironolactone) prescription medication with Blink Pharmacy. Same pills. Lower prices. No coupon req. Save on Spironolactone prescription medication with Blink Pharmacy. Same pills. Lower prices. No coupon req. 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